MoDOT officials closed a section of Interstate 70 near Highway 63 and the Lake of the Woods exit in Columbia because of the snow.
Interstate 70 conditions through Boone County were limited to one lane throughout most of the day because of drifting snow.
MoDOT officials said two major accidents caused traffic delays on Highway 63 in Columbia for about three hours this afternoon.
MoDOT crews are out in full force plowing snow and treating Missouri??s highways, but travel remains hazardous.
If you must travel, take your mobile phone and winter survival supplies.