The Columbia Fire Department responded to several 911 calls reporting a house and several cars on fire early Sunday morning.
Firefighters arrived at 3:32 a.m. to find a single-story home in the 2400 block of Carter Lane heavily involved in fire, with flames coming from the windows, roof and south end gable.
Three passenger cars were also on fire in the front yard.
Fire crews entered the house to search for occupants, but found no one inside.
It took twenty minutes to bring the blaze under control and extinguish both the house and the vehicles. Crews remained on the scene for approximately three hours.
Sixteen firefighters, three fire engines, a ladder truck and a rescue squad responded to the blaze.
The home sustained significant damage, with a damage estimate of $65,000.
Columbia Assistant Fire Marshal Brian Davison is investigating the cause, which has not been determined at this time.