Two people were seriously injured in a one-car crash Thursday night in Audrain County.
Missouri Highway Patrol said 54-year-old Kathy Cooper of Mexico lost control of her vehicle on Highway 54, almost at the Audrain-Callaway County line.
The car struck a culvert, crossed the median and hit another culvert before overturning.
Cooper and a passenger, 53-year-old Tamela Lofaro, also of Mexico, were flown to University Hospital in Columbia.
The accident occured shortly after 11 p.m. Thursday.